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Basic Pharmacokinetics And Pharmacodynamics: An Integrated Textbook And Computer Simulations
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- 作 者：Sara E. Rosenbaum
- 出 版 社：Wiley
- 出版时间：
- I S B N：9781119143154
- 页 数：576
- 所 属 分 类： 药学
- 供 货 周 期: 6
- 版 次：
- 字 数：
- 开 本：
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This book presents a comprehensive and thorough account of the essentials of contemporary pharmacokinetics and pharmacodynamics. The material is presented in a progressive and coordinated manner, providing a smooth transition from the fundamental concepts presented in the initial chapters through to the more advanced topics found in later chapters. The second edition updates key elements to reflect both the current state of knowledge in rapidly changing and evolving areas and newer applications of pharmacokinetics in clinical practice and drug development. Key areas of update include drug transporters, drug absorption, bioavailability, hepatic clearance and pharmacodynamics. Several of these updates have been carried out by well known experts. New chapters cover physiologically based pharmacokinetic modeling, the prediction of drug-drug interactions, and pharmacogenetics. A companion website contains interactive versions of all the PK and PD models, to allow students to experiment and observe the characteristics of the different models in a dynamic way. These interactive models also demonstrate the importance and influence of the different model parameters and the outcome when parameters change as a result of disease, concomitant drug, etc. Each chapter contains exercises based on the interactive models, which makes the book ideal for self-study.
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